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Chemical name 1-(2,5-dimethoxy-4-ethylphenyl)propan-2-amine
Chemical formula C13H21NO2
Molecular mass 223.32
Melting point 194-195 °C hydrochloride
CAS numbers 22004-32-6
Chemical structure of DOET

DOET, HECATE, or 2,5-dimethoxy-4-ethylamphetamine is an analogue of DOM, and is the three-carbon chain homologue to 2C-E. It produces hallucinogenic, psychedelic, and entheogenic effects.


DOET is in a class of compounds commonly known as alpha-methyl phenethylamines, or amphetamines and the full chemical name is 4-Ethyl-2,5-dimethoxy-alpha-methylbenzeneethanamine, or 1-(2,5-dimethoxy-4-ethylphenyl)propan-2-amine. It has an active stereocenter and (R)-DOET is the more active isomer.


DOET produces psychedelic and entheogenic effects that last up 14-20 hours. In his book PiHKAL, Alexander Shulgin lists a dosage of DOET as being 2-7 mg orally, with 6-7mg being the dosage for full, desired effects.


The mechanism that produces the hallucinogenic and entheogenic effects of DOET is thought to result from its action as an agonist at the 5-HT2A serotonin receptor.


The toxicity of DOET is not known.


DOET is classified as a Schedule 1 substance in the United States, and is similarly controlled in other parts of the world. Internationally, DOET is a Schedule I drug under the Convention on Psychotropic Substances[1].

See also

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