Psychology Wiki

Assessment | Biopsychology | Comparative | Cognitive | Developmental | Language | Individual differences | Personality | Philosophy | Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |

Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)

Chemical name 2-(8-bromo-2,3,6,7-tetrahydrofuro
Chemical formula C12H14BrNO2
Molecular mass 284.15 g/mol
Melting point 310 °C
CAS numbers 178557-21-6
Chemical structure of 2C-B-FLY

2C-B-FLY is a psychedelic phenethylamine of the 2C family. It was first synthesized by Aaron P. Monte, and sometimes used as an entheogen.


2C-B-FLY is 8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine. The full name of the chemical is 2-(8-bromo-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-4-yl)ethanamine.

In theory, dihydrodifuran analogues of any of the 2Cx / DOx family of drugs could be made, and would be expected to show similar activity to the parent compound. So in the same way that 2C-B-FLY is the dihydrodifuran analogue of 2C-B, the 8-iodo equivalent 2C-I-FLY would be the dihydrodifuran analogue of 2C-I, and the 8-methyl equivalent 2C-M-FLY would be the dihydrodifuran analogue of 2C-D.

Other related compounds can also be produced, where the alpha carbon of the ethylamine chain is methylated, the amphetamine derivative 3C-B-FLY would be made, this compound being the dihydrodifuran analogue of DOB, and would also be the unsaturated equivalent of Bromo-DragonFLY.

Where only one methoxy group of a 2Cx drug is cyclised into a dihydrofuran ring, the resulting compound is known as a "hemifly", and when an unsaturated furan ring is used the compound is known as a "hemi-dragonfly". A large family of compounds can thus be derived, many of which can be predicted to be active hallucinogens based on the known structure-activity relationships of these drugs, although most of these compounds have not yet been made and tested.

2C-B-FLY SAR.png


Alexander Shulgin lists a dosage of 2C-B-FLY at 10 mg orally.

However, various other information reveals that 2C-B-FLY is active as low as 1 mg [How to reference and link to summary or text].


2C-B-FLY produces psychedelic effects that last 6-8 hours, or up to 12 hours in larger doses.


2C-B-FLY is unscheduled and uncontrolled in the United States, but possession and sales of 2C-B-FLY could probably be prosecuted under the Federal Analog Act because of its structural similarities to 2C-B.


The hallucinogenic effect of 2C-B-FLY is mediated by its partial agonistic activity at the 5-HT2A serotonin receptor, but 2C-B-FLY also has a high binding affinity for the 5-HT2B and 5-HT2C serotonin receptor.


The toxicity of 2C-B-FLY is not known.


2C-B-FLY is unknown on the black market, though it is available from research chemical vendors that operate on the internet.

External links

This page uses Creative Commons Licensed content from Wikipedia (view authors).