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Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)
2C-B-FLY | |
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Chemical name | 2-(8-bromo-2,3,6,7-tetrahydrofuro [2,3-f][1]benzofuran-4-yl)ethanamine |
Chemical formula | C12H14BrNO2 |
Molecular mass | 284.15 g/mol |
Melting point | 310 °C |
CAS numbers | 178557-21-6 |
SMILES | NCCC1=C(OCC2)C2=C(Br)C3=C1CCO3 |
2C-B-FLY is a psychedelic phenethylamine of the 2C family. It was first synthesized by Aaron P. Monte, and sometimes used as an entheogen.
Chemistry[]
2C-B-FLY is 8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine. The full name of the chemical is 2-(8-bromo-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-4-yl)ethanamine.
In theory, dihydrodifuran analogues of any of the 2Cx / DOx family of drugs could be made, and would be expected to show similar activity to the parent compound. So in the same way that 2C-B-FLY is the dihydrodifuran analogue of 2C-B, the 8-iodo equivalent 2C-I-FLY would be the dihydrodifuran analogue of 2C-I, and the 8-methyl equivalent 2C-M-FLY would be the dihydrodifuran analogue of 2C-D.
Other related compounds can also be produced, where the alpha carbon of the ethylamine chain is methylated, the amphetamine derivative 3C-B-FLY would be made, this compound being the dihydrodifuran analogue of DOB, and would also be the unsaturated equivalent of Bromo-DragonFLY.
Where only one methoxy group of a 2Cx drug is cyclised into a dihydrofuran ring, the resulting compound is known as a "hemifly", and when an unsaturated furan ring is used the compound is known as a "hemi-dragonfly". A large family of compounds can thus be derived, many of which can be predicted to be active hallucinogens based on the known structure-activity relationships of these drugs, although most of these compounds have not yet been made and tested.
Dosage[]
Alexander Shulgin lists a dosage of 2C-B-FLY at 10 mg orally.
However, various other information reveals that 2C-B-FLY is active as low as 1 mg [How to reference and link to summary or text].
Effects[]
2C-B-FLY produces psychedelic effects that last 6-8 hours, or up to 12 hours in larger doses.
Legality[]
2C-B-FLY is unscheduled and uncontrolled in the United States, but possession and sales of 2C-B-FLY could probably be prosecuted under the Federal Analog Act because of its structural similarities to 2C-B.
Pharmacology[]
The hallucinogenic effect of 2C-B-FLY is mediated by its partial agonistic activity at the 5-HT2A serotonin receptor, but 2C-B-FLY also has a high binding affinity for the 5-HT2B and 5-HT2C serotonin receptor.
Dangers[]
The toxicity of 2C-B-FLY is not known.
Popularity[]
2C-B-FLY is unknown on the black market, though it is available from research chemical vendors that operate on the internet.
External links[]
Psychedelic phenethylamines
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Aleph • 2C-B • 2C-B-FLY • 2C-C • 2C-D • 2C-E • 2C-F • 2C-G • 2C-I • 2C-N • 2C-O • 2C-O-4 • 2C-P • 2C-T • 2C-T-2 • 2C-T-4 • 2C-T-7 • 2C-T-8 • 2C-T-9 • 2C-T-13 • 2C-T-15 • 2C-T-17 • 2C-T-21 • 2C-TFM • 3C-E • 3C-P • Br-DFLY • DESOXY • DMMDA-2 • DOB • DOC • DOET • DOI • DOM • DON • Escaline • Ganesha • HOT-2 • HOT-7 • HOT-17 • Isoproscaline • Lophophine • MDA • MMDA • MMDA-2 • MMDA-3a • MMDMA • Macromerine • Mescaline • Proscaline • TMA |
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