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|Alternative medical systems - edit|
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Alternative medicine describes practices used in place of conventional medical treatments. Complementary medicine describes practices used in conjunction and cooperation with conventional medicine, to assist the existing process. The term complementary and alternative medicine (CAM) is an umbrella term for both branches. CAM includes practices that incorporate spiritual, metaphysical, or religious underpinnings; non-European medical traditions, or newly developed approaches to healing.
The National Center for Complementary and Alternative Medicine defines complementary and alternative medicine as "a group of diverse medical and health care systems, practices, and products that are not presently considered to be part of conventional medicine". It also defines integrative medicine as "[combining] mainstream medical therapies and CAM therapies for which there is some high-quality scientific evidence of safety and effectiveness". Ralph Snyderman and Andrew Weil state "integrative medicine is not synonymous with complementary and alternative medicine (CAM). It has a far larger meaning and mission in that it calls for restoration of the focus of medicine on health and healing and emphasizes the centrality of the patient-physician relationship".
The list of therapies included under CAM changes gradually. If and when CAM therapies that are proven to be safe and effective become adopted into conventional health care, they gradually cease to be considered CAM, since adoption and acceptance often take time.
Approaches listed in APA Thesaurus
- Main article: List of branches of alternative medicine
Other definitions exist that are based on or include other criteria.
Marcia Angell, former editor-in-chief of the New England Journal of Medicine, takes exception to the above definition and relies on an "evidence-based" (EBM) definition, based on its relation to scientifically proven evidence of efficacy (or lack thereof). Angell states that "...since many alternative remedies have recently found their way into the medical mainstream [there] cannot be two kinds of medicine - conventional and alternative. There is only medicine that has been adequately tested and medicine that has not, medicine that works and medicine that may or may not work. Once a treatment has been tested rigorously, it no longer matters whether it was considered alternative at the outset. If it is found to be reasonably safe and effective, it will be accepted."
Others like George D. Lundberg, former editor of the Journal of the American Medical Association (JAMA), and Phil B. Fontanarosa, Senior Editor of JAMA, share Angell's use of an EBM definition. "There is no alternative medicine. There is only scientifically proven, evidence-based medicine supported by solid data or unproven medicine, for which scientific evidence is lacking. Whether a therapeutic practice is 'Eastern' or 'Western,' is unconventional or mainstream, or involves mind-body techniques or molecular genetics is largely irrelevant except for historical purposes and cultural interest. As believers in science and evidence, we must focus on fundamental issues-namely, the patient, the target disease or condition, the proposed or practiced treatment, and the need for convincing data on safety and therapeutic efficacy."
Richard Dawkins, Professor of the Public Understanding of Science at Oxford, also uses an EBM definition, defining alternative medicine as a "...set of practices which cannot be tested, refuse to be tested, or consistently fail tests. If a healing technique is demonstrated to have curative properties in properly controlled double-blind trials, it ceases to be alternative. It simply...becomes medicine." He also states that "There is no alternative medicine. There is only medicine that works and medicine that doesn't work."
These three commentators use a definition that is based on the objectively verifiable criteria of the scientific method, not one based on the changing curricula of various medical schools. According to them it is possible for a method to change categories (main stream vs. alternative) in either direction, based on increased knowledge of its effectiveness or lack thereof.
Well-known proponents of evidence-based medicine who study CAM, such as the Cochrane Collaboration and Edzard Ernst, Professor of Complementary Medicine at the University of Exeter, have retained CAM's generally-accepted (social) definition and do not define CAM as Dawkins, Angell and others do. Still, in their view, there can be "good CAM" or "bad CAM" based on evidentiary support.
Similarly, David M. Eisenberg relies on a "usage-based" definition, based on its inclusion in medical school curricula, and defines it as "medical interventions not taught widely at U.S. medical schools or generally available at U.S. hospitals."
The Alma-Alta declaration defines its strategy as "Health for All by 2000 A.D." through primary health care. This is in pursuance of the aims declared at the WHO/ UNICEF sponsored conference at Alma-Alta, USSR. Primary health care has been described as "essential health care based on practical, scientifically sound and socially accepted methods and technology made universally accessible to individuals and the families in the community through their full participation and at a cost that a community and country can afford to maintain at every stage of their development in the spirit of self reliance and self determination". Subsequently, the Alma-Alta declaration outlined that primary health care is based on training and scientific orientation provided to health care workers including physicians, nurses, midwives, auxiliary and community workers and traditional medical practitioners. Therefore, Medicina Alternativa has established guidelines and regulations outlining the code of ethics that healers are expected to follow consequent to their training, certification and membership of Medicina Alternativa.
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Jurisdiction differs concerning which branches of alternative medicine are legal, which are regulated, and which (if any) are provided by a government-controlled health service or reimbursed by a private health medical insurance company.
A number of alternative medicine advocates disagree with the restrictions of government agencies that approve medical treatments (such as the American Food and Drug Administration) and the agencies' adherence to experimental evaluation methods. They claim that this impedes those seeking to bring useful and effective treatments and approaches to the public, and protest that their contributions and discoveries are unfairly dismissed, overlooked or suppressed. Alternative medicine providers often argue that health fraud should be dealt with appropriately when it occurs.
In India, which is the home of several alternative systems of medicines, Ayurveda, Siddha, Unani, and Homeopathy are licenced by the government. Naturopathy will also be licensed soon because several Universities now offer bachelors degrees in it. Other activities connected with AM/CM, such as Panchakarma and massage therapy related to Ayurveda are also licenced by the government now.
Alternative systems of medicine in India do not have scientific decodation and standardization, so people has hasgitation to accept all therapies. same time persons who are angaged with practice of alternative medicine, those people also do practice of allopathic system of medicine. (Raju Dangar)
Contemporary use of alternative medicine
Edzard Ernst wrote in the Medical Journal of Australia that "about half the general population in developed countries use complementary and alternative medicine (CAM)". A survey released in May 2004 by the National Center for Complementary and Alternative Medicine, part of the National Institutes of Health in the United States, found that in 2002, 36% of Americans used some form of alternative therapy in the past 12 months — a category that included yoga, meditation, herbal treatments and the Atkins diet. If prayer was counted as an alternative therapy, the figure rose to 62.1%. Another study suggests a similar figure of 40%. A British telephone survey by the BBC of 1209 adults in 1998 shows that around 20% of adults in Britain had used alternative medicine in the past 12 months.[How to reference and link to summary or text]
The use of alternative medicine appears to be increasing, as a 1998 study showed that the use of alternative medicine had risen from 33.8% in 1990 to 42.1% in 1997. In the United Kingdom, a 2000 report ordered by the House of Lords suggested that "...limited data seem to support the idea that CAM use in the United Kingdom is high and is increasing."
Increasing numbers of medical colleges have begun offering courses in alternative medicine. For example, the University of Arizona College of Medicine offers a program in Integrative Medicine under the leadership of Dr. Andrew Weil which trains physicians in various branches of alternative medicine which "...neither rejects conventional medicine, nor embraces alternative practices uncritically." In three separate research surveys that surveyed 729 schools in the United States (125 medical schools offering an MD degree, 19 medical schools offering a Doctor of Osteopathy degree, and 585 schools offering a nursing degree), 60% of the Allopathic medical schools, 95% of Osteopathic medical schools and 84.8% of the nursing schools teach some form of CAM. A number of independent and private institutions offering courses in alternative medicine have also emerged, including the Upledger Institute and the International Alliance of Healthcare Educators (IAHE). Accredited Naturopathic colleges and universities are increasing in number and popularity in the U.S.A. They offer the most complete medical training in complimentary medicines that is available today[How to reference and link to summary or text]. See Naturopathic medicine.
In the UK, no medical schools offer courses that teach the clinical practice of alternative medicine. However, alternative medicine is taught in several schools as part of the curriculum. Teaching is based mostly on theory and understanding alternative medicine, with emphasis on being able to communicate with alternative medicine specialists. To obtain competence in practicing clinical alternative medicine, qualifications must be obtained from individual medical societies. The student must have graduated and be a qualified doctor. The British Medical Acupuncture Society, which offers medical acupuncture certificates to doctors, is one such example, as is the College of Naturopathic Medicine UK and Ireland.
The NCCAM surveyed the American public on complementary and alternative medicine use in 2002. According to the survey:
- 36 percent of U.S. adults age 18 years and over use some form of complementary and alternative medicine (CAM).
- When prayer specifically for health reasons is included in the definition of CAM, the number of adults using some form of CAM in 2002 rose to 62 percent.
- The majority of individuals (54.9%) used CAM in conjunction with conventional medicine.
- Most people use CAM to treat and/or prevent musculoskeletal conditions or other conditions associated with chronic or recurring pain.
- "The fact that only 14.8% of adults sought care from a licensed or certified CAM practitioner suggests that most individuals who use CAM prefer to treat themselves."
- "Women were more likely than men to use CAM. The largest sex differential is seen in the use of mind-body therapies including prayer specifically for health reasons".
- "Except for the groups of therapies that included prayer specifically for health reasons, use of CAM increased as education levels increased".
- The most common CAM therapies used in the USA in 2002 were prayer (45.2%), herbalism (18.9%), breathing meditation (11.6%), meditation (7.6%), chiropractic medicine (7.5%), yoga (5.1%), body work (5.0%), diet-based therapy (3.5%), progressive relaxation (3.0%), mega-vitamin therapy (2.8%) and Visualization (2.1%)
Support for alternative medicine
Advocates of alternative medicine hold that alternative therapies often provide the public with services not available from conventional medicine. This argument covers a range of areas, such as patient empowerment, alternative methods of pain management, treatment methods that support the biopsychosocial model of health, stress reduction services, other preventive health services that are not typically a part of conventional medicine, and of course complementary medicine's palliative care which is practiced by such world renowned cancer centers such as Memorial Sloan-Kettering.
Salient features of alternative medicines
Advocates of alternative medicine hold that the various alternative treatment methods are effective in treating a wide range of major and minor medical conditions, and contend that recently published research (such as Michalsen, 2003, Gonsalkorale 2003, and Berga 2003) proves the effectiveness of specific alternative treatments. They assert that a PubMed search revealed over 370,000 research papers classified as alternative medicine published in Medline-recognized journals since 1966 in the National Library of Medicine database. See also Kleijnen 1991, and Linde 1997.
Advocates of alternative medicine hold that alternative medicine may provide health benefits through patient empowerment, by offering more choices to the public, including treatments that are simply not available in conventional medicine:
- "Most Americans who consult alternative providers would probably jump at the chance to consult a physician who is well trained in scientifically based medicine and who is also open-minded and knowledgeable about the body's innate mechanisms of healing, the role of lifestyle factors in influencing health, and the appropriate uses of dietary supplements, herbs, and other forms of treatment, from osteopathic manipulation to Chinese and Ayurvedic medicine. In other words, they want competent help in navigating the confusing maze of therapeutic options that are available today, especially in those cases in which conventional approaches are relatively ineffective or harmful."
It must be added though that most practitioners do not hold a degree in official medicine or even have a solid understanding of scientific principles, as can be deduced from many of their publications. And, of course, the fact of providing more choice has no bearing whatsoever as to the efficacy of the proposed treatment.
Although advocates of alternative medicine acknowledge that the placebo effect may play a role in the benefits that some receive from alternative therapies, they point out that this does not diminish their validity. Researchers who judge treatments using the scientific method are concerned by this viewpoint, since, according to standard controlled studies, it is an acknowledgement of the inefficacy of alternative treatments.
Danger reduced when used as a complement to conventional medicine
A major objection to alternative medicine is that it may be done in place of conventional medical treatments. As long as alternative treatments are used alongside standard conventional medical treatments, most medical doctors find most forms of complementary medicine acceptable. Consistent with previous studies, the CDC recently reported that the majority of individuals in the United States (i.e., 54.9%) used CAM in conjunction with conventional medicine.[How to reference and link to summary or text]
Patients should however always inform their medical doctor they are using alternative medicine. Some patients do not tell their medical doctors since they fear it will hurt their patient-doctor relationship. Some alternative treatments may interact with orthodox medical treatments, and ideally, such conflicts should be explored in the interest of the patient. However, many conventional practitioners are biased or uninformed about alternatives, and the exhortations to disclose alternative treatments to one's doctor do not address the complexities involved.
The issue of alternative medicine interfering with conventional medical practices is minimized when it is only turned to after the conventional medicine path has been exhausted. Many patients believe alternative medicine can help in coping with chronic illnesses for which conventional medicine offers no cure and only management. It is becoming more common for a patient's own MD to suggest alternatives when they cannot offer a treatment.
Supporters of alternative medicine
- Kevin Trudeau
- Joseph Mercola
Criticism of alternative medicine
See also List of branches of alternative medicine for specific criticisms of different types of CAM
Due to the wide range of therapies that are considered to be "alternative medicine" few criticisms apply across the board, except possibly that of not being scientifically supported or even testable. Criticisms directed at specific branches of alternative medicine range from the fairly minor (conventional treament is believed to be more effective in a particular area) to incompatibility with the known laws of physics (for example, in homeopathy). Critics argue that alternative medicine practitioners may not have an accredited medical degree or be licensed physicians or general practitioners and make sweeping claims without demonstrated expertise. This cannot always be considered a serious criticism, because unless a new system of medicine becomes established, it does not receive accreditation of any kind, except by its own professional organizations. This is the route homeopathy, ayurveda, siddha, unani, and naturopathy had to follow in those countries where it is now offered by accredited institutions. Proponents of the various forms of alternative medicine reject criticism as being founded in prejudice, financial self-interest, or ignorance. Refutations of criticism sometimes take the form of an appeal to nature.
Lack of proper testing
- Main article: Evidence-based medicine
Evidence-based medicine (EBM) applies the scientific method to medical practice, and aims for the ideal that healthcare professionals should make "conscientious, explicit, and judicious use of current best evidence" in their everyday practice. Prof. Edzard Ernst is a notable proponent of applying EBM to CAM.
Although proponents of alternative medicine often cite the large number of studies which have been performed, critics point out the fact that there are no statistics on exactly how many of these studies were controlled, double-blind peer-reviewed experiments or how many produced results supporting alternative medicine or parts thereof. They contend that many forms of alternative medicine are rejected by conventional medicine because the efficacy of the treatments has not been demonstrated through double-blind randomized controlled trials; this is not a moot point, since all conventional drugs reach the market only after such trials have proved their efficacy. One is led to wonder why whole categories of drugs or treatments should be excused from these routine tests. Also, some skeptics of alternative practices point out that a person may attribute symptomatic relief to an otherwise ineffective therapy due to the natural recovery from or the cyclical nature of an illness (the regression fallacy), the placebo effect, or the possibility that the person never originally had a true illness.
Problems with known tests and studies
Critics contend that observer bias and poor study design invalidate the results of many studies carried out by alternative medicine promoters.
A review of the effectiveness of certain alternative medicine techniques for cancer treatment, while finding that most of these treatments are not merely "unproven" but are proven not to work, notes that several studies have found evidence that the psychosocial treatment of patients by psychologists is linked to survival advantages (although it comments that these results are not consistently replicated). The same review, while specifically noting that "complementary therapies for cancer-related symptoms were not part of this review", cites studies indicating that several complementary therapies can provide benefits by, for example, reducing pain and improving the mood of patients.
Some argue that less research is carried out on alternative medicine because many alternative medicine techniques cannot be patented, and hence there is little financial incentive to study them. Drug research, by contrast, can be very lucrative, which has resulted in funding of trials by pharmaceutical companies. Many people, including conventional and alternative medical practitioners, contend that this funding has led to corruption of the scientific process for approval of drug usage, and that ghostwritten work has appeared in major peer-reviewed medical journals. Increasing the funding for research of alternative medicine techniques was the purpose of the National Center for Complementary and Alternative Medicine. NCCAM and its predecessor, the Office of Alternative Medicine, have spent more than $200 million on such research since 1991. The German Federal Institute for Drugs and Medical Devices Commission E has studied many herbal remedies for efficacy.
Critics contend that some people have been hurt or killed directly from the various practices or indirectly by failed diagnoses or the subsequent avoidance of conventional medicine which they believe is truly efficacious.
Alternative medicine critics agree with its proponents that people should be free to choose whatever method of healthcare they want, but stipulate that people must be informed as to the safety and efficacy of whatever method they choose. People who choose alternative medicine may think they are choosing a safe, effective medicine, while they may only be getting quack remedies. Grapefruit seed extract is an example of quackery when multiple studies demonstrate its universal antimicrobial effect is due to synthetic antimicrobial contamination.
Delay in seeking conventional medical treatment
They state that those who have had success with one alternative therapy for a minor ailment may be convinced of its efficacy and persuaded to extrapolate that success to some other alternative therapy for a more serious, possibly life-threatening illness. For this reason, they contend that therapies that rely on the placebo effect to define success are very dangerous.
Danger can be increased when used as a complement to conventional medicine
A Norwegian multicentre study examined the association between the use of alternative medicines (AM) and cancer survival. 515 patients using standard medical care for cancer were followed for eight years. 22% of those patients used AM concurrently with their standard care. The study revealed that death rates were 30% higher in AM users than in those who did not use AM: "The use of AM seems to predict a shorter survival from cancer."
Associate Professor Alastair MacLennan of the Department of Obstetrics and Gynaecology in Adelaide University, Australia reports that a patient of his almost bled to death on the operating table. She had failed to mention she had been taking "natural" potions to "build up her strength" for the operation - one of them turned out to be a powerful anticoagulant which nearly caused her death.[How to reference and link to summary or text]
Danger from undesired side-effects
Conventional treatments are thoroughly checked for undesired side-effects, whereas alternative treatments are normally not. Any alternative treatment that has a biological or psychological impact may also have potentially dangerous biological or psychological side-effects. Attempts to refute this sometimes use the appeal to nature fallacy, i.e. "that which is natural cannot be harmful".
Ironically, a therapy such as homeopathy which, in the eyes of all known physics and chemistry, cannot possibly have more effect on the patient than simple water does, is surely safe from all side effects considerations.
Similar problems as those related to self-medication also apply to parts of alternative medicine. For example, an alternative medicine may instantly make problems better, but actually worsen problems in the long run. The result may be addiction[How to reference and link to summary or text] and deteriorating health.
Issues of regulation
Critics contend that some branches of alternative medicine are often not properly regulated in some countries to identify who practices or know what training or expertise they may possess. Critics argue that the governmental regulation of any particular alternative therapy does necessitate that the therapy is effective. The most sensible course in such a case could be to simply ensure that the sold treatment is not dangerous, but the problem would then remain to know if it does what its proponents say it does.
Critics of alternative medicine
- Further information: Glossary of alternative medicine terms
Integrative medicine is a branch of alternative medicine which limits itself to methods with strong scientific evidence of efficacy and safety. The main proponent of integrative medicine is Andrew T. Weil M.D., who founded the Program in Integrative Medicine at the University of Arizona in 1994 based on a phrase coined by Elson Haas, MD. Responsible alternative health product providers who have had medical studies conducted on their products often publish these studies online. Even so, it is wise to ask for a list of the ingredients used in the products you are considering purchasing.
- Faith healing
- Folk medicine
- Holistic health
- Physical treatment methods
- Medical treatments (general)
- Medicinal herbs and plants
- Preventative medicine
- Transcultural psyciatry
- What is Complementary and Alternative Medicine (CAM)?. URL accessed on 2006-07-11.
- Snyderman, R.; Weil, A. T. (2002-02-25). "Integrative Medicine: Bringing Medicine Back To Its Roots". Archives of Internal Medicine. Retrieved on 2006-07-11. PMID 11863470
- alternative medicine Function: noun: "any of various systems of healing or treating disease (as chiropractic, homeopathy, or faith healing) not included in the traditional medical curricula taught in the United States and Britain." ; retrieved from Merriam-Webster Online on 5 August 2006.
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- Alternative medicine meets science. Fontanarosa P.B., and Lundberg G.D. JAMA. 1998; 280: 1618-1619.
- Simonyi Professorship web site
- A callous world. Richard Holloway. Book review Richard Dawkins A Devil's Chaplain. The Guardian, February 15, 2003.
- Dawkins, Richard (003). A Devil's Chaplain, Weidenfeld & Nicolson.
- The Cochrane Collaboration Complementary Medicine Field, www.compmed.umm.edu/Cochrane/index.html. Retrieved 5 August 2006.
- The HealthWatch Award 2005: Prof. Edzard Ernst Complementary medicine: the good the bad and the ugly. www.healthwatch-uk.org/awardwinners/edzardernst.html, retrieved 5 August 2006
- "Complementary medicine is diagnosis, treatment and/or prevention which complements mainstream medicine by contributing to a common whole, by satisfying a demand not met by orthodoxy or by diversifying the conceptual frameworks of medicine." Ernst et al British General Practitioner 1995; 45:506
- Unconventional Medicine in the United States -- Prevalence, Costs, and Patterns of Use. Eisenberg D, et al. N Engl J Med 1993; 328:246-252.
- Ernst E. "Obstacles to research in complementary and alternative medicine." Medical Journal of Australia, 2003; 179'(6): 279-80. PMID 12964907 MJA online
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- Eisenberg, DM, Davis RB, Ettner SL "Trends in alternative medicine use in the United States 1990-1997." JAMA, 1998; 280:1569-1575. PMID 9820257
- House of Lords report on CAM
- University of Arizona position on Alternative Medicine
- Wetzel MS, Eisenberg DM, Kaptchuk TJ. "Courses involving complementary and alternative medicine at US medical schools." JAMA 1998; 280(9):784 -787. PMID 9729989
- Saxon DW, Tunnicliff G, Brokaw JJ, Raess BU. "Status of complementary and alternative medicine in the osteopathic medical school curriculum." J Am Osteopath Assoc 2004; 104(3):121-6. PMID 15083987
- Fenton MV, Morris DL. "The integration of holistic nursing practices and complementary and alternative modalities into curricula of schools of nursing." Altern Ther Health Med, 2003; 9(4):62-7. PMID 12868254
- Barnes, P. M.; Powell-Griner, E.; McFann, K.; Nahin, R. L. (2004). "Complementary and Alternative Medicine Use Among Adults: United States, 2002". National Center for Health Statistics.
- Vickers A. "Alternative Cancer Cures: "Unproven" or "Disproven"?" CA Cancer J Clin 2004; 54: 110-118. Online
- Michalsen A, Ludtke R, Buhring M. "Thermal hydrotherapy improves quality of life and hemodynamic function in patients with chronic heart failure." Am Heart J, 2003; 146(4):E11. PMID 14564334
- Gonsalkorale WM, Miller V, Afzal A, Whorwell PJ. "Long term benefits of hypnotherapy for irritable bowel syndrome." Gut, 2003; 52(11):1623-9. PMID 14570733
- Berga SL, Marcus MD, Loucks TL. "Recovery of ovarian activity in women with functional hypothalamic amenorrhea who were treated with cognitive behavior therapy." Fertility and Sterility 2003; 80(4): 976-981 Abstract
- Kleijnen J, Knipschild P, ter Riet G. "Clinical trials of homoeopathy." BMJ, 1991; 302:316-23. Erratum in: BMJ, 1991;302:818. PMID 1825800
- Linde K, Clausius N, Ramirez G. "Are the clinical effects of homeopathy placebo effects? A meta-analysis of placebo-controlled trials." Lancet, 1997; 350: 834-43. Erratum in: Lancet 1998 Jan 17;351(9097):220. PMID 9310601
- Snyderman R & Weil AT. "Integrative medicine: bringing medicine back to its roots." Arch Intern Med 2002; 162:395–397.
- James Alcock PhD, Alternative Medicine and the Psychology of Belief, The Scientific Review of Alternative Medicine, Fall/Winter 1999 Volume 3 ~ Number 2. available online
- Larkin M. "Whose article is it anyway?" Lancet, 1999; 354:136. Editorial
- Flanagin A, Carey LA, Fontanarosa PB. "Prevalence of articles with honorary authors and ghost authors in peer-reviewed medical journals." JAMA, 1998; 280(3):222-4. Full text
- CSICOP.org article on alternative medicine
- Ganzera M, Aberham A, Stuppner H. Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract. Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria. J Agric Food Chem. 2006 May 31;54(11):3768-72. Abstract
- Takeoka, G., Dao, L., Wong, R.Y., Lundin, R., Mahoney N. Identification of benzethonium chloride in commercial grapefruit seed extracts. J Agric Food Chem. 2001 49(7):3316–20. Abstract
- von Woedtke, T., Schlüter, B., Pflegel, P., Lindequist, U.; Jülich, W.-D. Aspects of the antimicrobial efficacy of grapefruit seed extract and its relation to preservative substances contained. Pharmazie 1999 54:452–456. Abstract
- Sakamoto, S., Sato, K., Maitani, T., Yamada, T. Analysis of components in natural food additive “grapefruit seed extract” by HPLC and LC/MS. Bull. Natl. Inst. Health Sci. 1996, 114:38–42. Abstract
- Takeoka, G.R., Dao, L.T., Wong, R.Y., Harden L.A. Identification of benzalkonium chloride in commercial grapefruit seed extracts. J Agric Food Chem. 2005 53(19):7630–6. Abstract
- Risberg T, et al. Does use of alternative medicine predict survival from cancer? Eur J Cancer 2003 Feb;39(3):372-7 
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- Benedetti F, Maggi G, Lopiano L. "Open Versus Hidden Medical Treatments: The Patient's Knowledge About a Therapy Affects the Therapy Outcome." Prevention & Treatment, 2003; 6(1), APA online
- Downing AM, Hunter DG. "Validating clinical reasoning: a question of perspective, but whose perspective?" Man Ther, 2003; 8(2): 117-9. PMID 12890440 Manual Therapy Online
- Eisenberg DM. "Advising patients who seek alternative medical therapies." Ann Intern Med 1997; 127:61-69. PMID 9214254
- Gunn IP. "A critique of Michael L. Millenson's book, Demanding medical excellence: doctors and accountability in the information age, and its relevance to CRNAs and nursing." AANA J, 1998 66(6):575-82. Review. PMID 10488264
- Tonelli MR. "The limits of evidence-based medicine." Respir Care, 2001; 46(12): 1435-40; discussion 1440-1. Review. PMID 11728302 PMID: 11863470
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World Health Organization publication
Journals dedicated to alternative medicine research
- Alternative therapies in health and medicine. Aliso Viejo, CA : InnoVision Communications, c1995- NLM ID: 9502013
- Alternative medicine review : a journal of clinical therapeutic. Sandpoint, Idaho : Thorne Research, Inc., c1996- NLM ID: 9705340
- BMC complementary and alternative medicine. London : BioMed Central, 2001- NLM ID: 101088661
- Complementary therapies in medicine. Edinburgh ; New York : Churchill Livingstone, c1993- NLM ID: 9308777
- Evidence based complementary and alternative medicine
- Evidence Based journal of Integrative medicine
- Journal of Integrative medicine.
- The journal of alternative and complementary medicine : research on paradigm, practice, and policy. New York, NY : Mary Ann Liebert, Inc., c1995- NLM ID: 9508124
- Journal of alternative & complementary medicine. London : Argus Health Publications, c1989- NLM ID: 9883124
- Journal for Alternative and Complementary Medicine
- Scientific Review of Alternative Medicine (SRAM)
Other works that discuss alternative medicine
- Ninivaggi, F. J., An Elementary Textbook of Ayurveda: Medicine with a Six Thousand Year Old Tradition, International Universities/Psychosocial Press, Madison, CT, 2001.
- Diamond, J. Snake Oil and Other Preoccupations, 2001, ISBN 0-09-942833-4 , foreword by Richard Dawkins reprinted in Dawkins, R., A Devil's Chaplain, 2003, ISBN 0-7538-1750-0 .
- Rosenfeld, Anna, Where Do Americans Go for Healthcare?", Case Western Reserve University, Cleveland, Ohio, USA.
- Planer, Felix E. 1988 Superstition, Revised ed. Buffalo, New York: Prometheus Books
- Hand, Wayland D. 1980 "Folk Magical Medicine and Symbolism in the West", in Magical Medicine, Berkeley: University of California Press, pp. 305-319.
- Phillips Stevens Jr. Nov./Dec. 2001 "Magical Thinking in Complementary and Alternative Medicine", Skeptical Inquirer Magazine, Nov.Dec 2001
- Illich, Ivan. Limits to Medicine. Medical Nemesis: The expropriation of Health. Penguin Books, 1976.
- Dillard, James and Terra Ziporyn. Alternative Medicine for Dummies. Foster City, CA: IDG Books Worldwide, Inc., 1998.
- Pert, Candace B., Molecules of Emotion: Why You Feel the Way You Feel, Scribners, 1997, ISBN 0-684-84634-9
- Trudeau, Kevin, Natural Cures "They" Don't Want You to Know About , Alliance Publishing Group, ISBN 0-9755995-9-3; Mass Market Edition, 2007.
- Trudeau, Kevin, More Natural "Cures" Revealed, Alliance Publishing Group, 2006, ISBN 0-9755995-4-2.
- Wisneski, Leonard A. and Lucy Anderson, The Scientific Basis of Integrative Medicine, CRC Press, 2005. ISBN 0-8493-2081-X.
- NCCAM, Get The Facts, What is Complementary and Alternative Medicine
- The National Center for Complementary and Alternative Medicine - US National Institutes of Health
- Alternative Cancer Information - Hub of Peer-Reviewed literature on Prevention of Metastasis for Patients Diagnosed with Cancer
- Complementary and Alternative Medicine on PubMed - Alternative Medicine Research Database
- Natural Medicines Comprehensive Database - Evidence-Based, Clinical Information on Natural Medicines
- Web pages for new BBC/Open University television series "Alternative Medicine" that examines the evidence scientifically.
- The British Library - finding information on the complementary medicines industry
- Philippine Herbs Healing Wonders A guide to the effective use of Philippine Medicinal Plants
- Metatheory of Medicine: A Lay Perspective by Ken Renshaw
- Omega 3 supplements
- A Different Way to Heal? and Videos - PBS, Scientific American Frontiers Web Feature
- What is Complementary and Alternative Medicine? - By Steven Novella MD
- Skepdic Article on Alternative Medicine
- Who Gets to Validate Alternative Medicine - PBS article
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