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Blood volume is the volume of blood (both red blood cells and plasma) in a person's circulatory system. A typical adult has a blood volume of approximately between 4.7 and 5 litres, with females generally having less blood volume than males. [1]. Blood volume is regulated by the kidneys.

Blood volume (BV) can be calculated given the hematocrit (HC; the fraction of blood that is red blood cells) and plasma volume (PV):

Diagnostic technologies are commercially available to measure human blood volume. A recent radionucleotide study called BVA-100, Blood Volume Analysis is the only FDA approved instrument that provides a measure of Red Blood Cells and Plasma with 98% accuracy.

Blood volume measurement is indicated for the diagnosis and treatment patients suffering from Congestive Heart Failure, Chronic Hypertension, Renal Failure and Critical Care.


  1. Lee, Lan Na (1998). Volume of Blood in a Human. The Physics Factbook.

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