Centrophenoxine

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Centrophenoxine chemical structure Centrophenoxine
IUPAC name
CAS number 51-68-3	ATC code [[ATC_code_|]][1]
PubChem 4039	DrugBank [2]
Chemical formula	C12H16ClNO3
Molecular weight	257.713
Bioavailability
Metabolism
Elimination half-life
Excretion
Pregnancy category
Legal status
Routes of administration

Centrophenoxine (also called Meclofenoxate, and formerly sold under the brand name Lucidril®) is a drug used to treat the symptoms of senile dementia and Alzheimer's Disease. It is a compound of two biochemicals: dimethylaminoethanol (DMAE) and parachlorophenoxyacetate (pCPA). DMAE is a natural substance, found especially in fish, and also produced in the human brain. pCPA is a synthetic compound that resembles to a variety of plant hormones called auxins.

Like DMAE, it is a precursor to the neurotransmitter acetylcholine and may increase levels of this chemical in the CNS. It is reported to improve memory and general cognition.

It is also used off-label as a nootropic, often combined with a racetam drug such as piracetam.

Side Effects & Contraindications

Possible side effects may include nausea or mild dizziness. People with severely high blood pressure or convulsive disorders such as epilepsy should avoid Centrophenoxine. ^[1] Large doses may cause tight jaw clenching.

References

1. Centrophenoxine Page @ The American Academy of Anti-Aging Medicine

External links

• Collection of Scientific Abstracts on Centrophenoxine
• Brain Research and Information Network B.R.A.I.N.

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