Clinical research methods

Please expand this article.
There may be more info on the talk page or at Requests for expansion.
Please remove this message once the article has been expanded.

There are many different clinical research methods.

v·d·e Biomedical research: Clinical study design / Design of experiments
Overview	Clinical trial • Clinical trial protocol • Clinical study design
Controlled study (EBM I to II-1; A to B)	Randomized controlled trial (Blind experiment, Open-label trial)
Observational study (EBM II-2 to II-3; B to C)	Cross-sectional study vs. Longitudinal study, Ecological study Cohort study (Retrospective cohort study, Prospective cohort study) Case-control study (Nested case-control study) Case series Case study Case report
Epidemiology/ methods	occurrence: Incidence (Cumulative incidence) Prevalence (Point prevalence, Period prevalence) association: absolute (Absolute risk reduction, Attributable risk, Attributable risk percent) relative (Relative risk, Odds ratio, Hazard ratio) other: Virulence • Infectivity • Mortality rate • Morbidity • Case fatality • Specificity and sensitivity • Likelihood-ratios • Pre/post-test probability
Trial/test types	In vitro • In vivo • Animal testing • Animal testing on non-human primates • First-in-man study • Multicenter trial • Seeding trial • Vaccine trial
Analysis of clinical trials	Risk–benefit analysis • Systematic review • Meta-analysis
Interpretation of results	Selection bias • Correlation does not imply causation • Null result
Category • Glossary • List of topics