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A dopamine agonist is a compound that activates dopamine receptors, mimicking the effect of the neurotransmitter dopamine.
Uses[]
Some medical drugs act as dopamine agonists; they are typically used for treating Parkinson's disease and certain pituitary tumors (prolactinomas), and may be useful for restless legs syndrome (RLS). Both Requip (Ropinirole) and Mirapex (Pramipexole) are FDA approved for the treatment of RLS.
There is also an ongoing clinical trial to test the effectiveness of Requip (ropinirole), a dopamine agonist, in reversing the symptoms of SSRI induced sexual dysfunction. [1]
Examples[]
Examples of dopamine agonists include:
- Parlodel (bromocriptine)
- Dostinex (cabergoline)
- Permax (pergolide) - Removed from market March 29,2007.[2]
- Mirapex (pramipexole)
- Requip (ropinirole)
- Apokyn (apomorphine)
- Neupro (rotigotine)
See also[]
References[]
- ↑ ClinicalTrials.gov NCT00334048 - "Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo"
- ↑ FDA Announces Voluntary Withdrawal of Pergolide Products
External links[]
Anti-parkinson drugs: dopaminergic agents (N04B) | |
|---|---|
| Dopa and derivatives |
Levodopa, Melevodopa, Etilevodopa |
| Adamantane derivatives | |
| Dopamine agonists |
Apomorphine, Bromocriptine, Cabergoline, Dihydrexidine, Dihydroergocryptine mesylate, Fenoldopam, Lisuride, Pergolide, Piribedil, Pramipexole, Quinpirole, Ropinirole, Rotigotine, SKF 38393, SKF 82958 |
| MAOIs | |
| Other |
Tolcapone, Entacapone, Budipine |
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