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in: Dopamine agonists, Drugs

Dopamine agonists

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Dopamine2

Dopamine

A dopamine agonist is a compound that activates dopamine receptors, mimicking the effect of the neurotransmitter dopamine.

Uses[]

Some medical drugs act as dopamine agonists; they are typically used for treating Parkinson's disease and certain pituitary tumors (prolactinomas), and may be useful for restless legs syndrome (RLS). Both Requip (Ropinirole) and Mirapex (Pramipexole) are FDA approved for the treatment of RLS.

There is also an ongoing clinical trial to test the effectiveness of Requip (ropinirole), a dopamine agonist, in reversing the symptoms of SSRI induced sexual dysfunction. [1]

Examples[]

Examples of dopamine agonists include:

See also[]

References[]

  1. ↑ ClinicalTrials.gov NCT00334048 - "Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo"
  2. ↑ FDA Announces Voluntary Withdrawal of Pergolide Products

External links[]


v·d·e
Anti-parkinson drugs: dopaminergic agents (N04B)
Dopa and derivatives

Levodopa, Melevodopa, Etilevodopa

Adamantane derivatives

Amantadine

Dopamine agonists

Apomorphine, Bromocriptine, Cabergoline, Dihydrexidine, Dihydroergocryptine mesylate, Fenoldopam, Lisuride, Pergolide, Piribedil, Pramipexole, Quinpirole, Ropinirole, Rotigotine, SKF 38393, SKF 82958

MAOIs

Selegiline, Rasagiline

Other

Tolcapone, Entacapone, Budipine

v·d·e
Receptor agonists, antagonists, and reuptake inhibitors
Dopamine receptor

Dopamine agonist • Dopamine antagonist • Dopamine reuptake inhibitor

5-HT (serotonin) receptor

Serotonin receptor agonist • Serotonin antagonist (5-HT3) • Serotonin uptake inhibitor (SSRI)

Adrenergic receptor

Adrenergic agonist (Alpha, Beta2) • Adrenergic antagonist (Alpha, Beta) • Adrenergic uptake inhibitor

Acetylcholine receptor

Cholinergic (Muscarinic, Nicotinic) • Anticholinergic (Muscarinic, Nicotinic) • Acetylcholinesterase inhibitor

Histamine receptor

Histamine agonist • Histamine antagonist (H1, H2)

GABA receptor

GABA agonist • GABA antagonist

NMDA receptor

NMDA receptor antagonist



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