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Globulin is one of the two types of serum proteins, the other being albumin. This generic term encompasses a heterogeneous series of families of proteins, with larger molecules and less soluble in pure water than albumin, which migrate less than albumin during serum electrophoresis. The normal range in blood is 2 to 3.5 g/dl.
It is sometimes used synonymously with globular protein. However, albumin is also a globular protein, but not a globulin. All other serum globular proteins are globulins.
Protein electrophoresis is used to categorize globulins into the following four categories:
- Alpha 1 globulins
- Alpha 2 globulins
- Beta globulins
- Gamma globulins (one group of gamma globulins are immunoglobulins, that function as antibodies)
Reference ranges for blood tests, comparing blood content of globulins (shown in purple at right) with other constituents.
See also[]
- Glucoproteins
External links[]
Proteins |
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Protein biosynthesis - Posttranslational modification - Protein folding - Protein structure - Protein structural domains - Protein targeting - Proteome - Protein methods - Proteasome List of types of proteins - List of proteins - Membrane protein - Globular protein - Fibrous protein |
Proteins: globulins | |
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| Serum |
Alpha globulins -Beta globulins - Gamma globulin (Immunoglobulins) - Fibronectins - Macroglobulins - Transcobalamins |
| Other |
Beta-lactoglobulin (Lactoferrin) - Thyroglobulin - Alpha-lactalbumin |
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