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- The correct title of this article is NaV1.4. It features superscript or subscript characters that are substituted or omitted because of technical limitations.
| sodium channel, voltage-gated, type IV, alpha | |
|---|---|
| Symbol(s): | SCN4A HYKPP, Nav1.4 |
| Locus: | 17 q23 -q25.3 |
| EC number | [1] |
| EntrezGene | 6329 |
| OMIM | 603967 |
| RefSeq | NM_000334 |
| UniProt | P35499 |
The Nav1.4 sodium ion channel protein is encoded by the SCN4A gene. Mutations in the gene are associated with hyperkalemic periodic paralysis, paramyotonia congenita, and potassium-aggravated myotonia.
Membrane transport protein: ion channels
| |
|---|---|
| Ca | Voltage-dependent calcium channel (L-type/CACNA1C, N-type, P-type, Q-type, R-type, T-type) - Inositol triphosphate receptor - Ryanodine receptor - Cation channels of sperm |
| Na: Sodium channel | Nav1.4 - Nav1.5 - Nav1.7 - Epithelial sodium channel |
| K: Potassium channel | Voltage-gated (KvLQT1, KvLQT2, KvLQT3, HERG, Shaker gene, KCNE1) - Calcium-activated (BK channel, SK channel) - Inward-rectifier (ROMK, KCNJ2) - Tandem pore domain |
| Cl: Chloride channel | Cystic fibrosis transmembrane conductance regulator |
| Porin | Aquaporin (1, 2, 3, 4) |
| Transient receptor potential | TRPA - TRPC (TRPC6) - TRPM (TRPM6) - TRPML (Mucolipin-1) - TRPP - TRPV (TRPV1, TRPV6) |
| Other/general | Gap junction - Stretch-activated ion channel - Ligand-gated ion channel - Voltage-gated ion channel - Cyclic nucleotide-gated ion channel - Two-pore channel |
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