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Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)
| sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) | |
|---|---|
| Symbol(s): | SCN5A LQT3, CMD1E, Nav1.5 |
| Locus: | 3 p21 |
| EC number | [1] |
| EntrezGene | 6331 |
| OMIM | 600163 |
| RefSeq | NM_198056 |
| UniProt | Q14524 |
The Nav1.5 sodium ion channel protein is encoded by the SCN5A gene. Mutations in the gene are associated with long QT syndrome type 3 (LQT3), Brugada syndrome, and idiopathic ventricular fibrillation.
Membrane transport protein: ion channels
| |
|---|---|
| Ca | Voltage-dependent calcium channel (L-type/CACNA1C, N-type, P-type, Q-type, R-type, T-type) - Inositol triphosphate receptor - Ryanodine receptor - Cation channels of sperm |
| Na: Sodium channel | Nav1.4 - Nav1.5 - Nav1.7 - Epithelial sodium channel |
| K: Potassium channel | Voltage-gated (KvLQT1, KvLQT2, KvLQT3, HERG, Shaker gene, KCNE1) - Calcium-activated (BK channel, SK channel) - Inward-rectifier (ROMK, KCNJ2) - Tandem pore domain |
| Cl: Chloride channel | Cystic fibrosis transmembrane conductance regulator |
| Porin | Aquaporin (1, 2, 3, 4) |
| Transient receptor potential | TRPA - TRPC (TRPC6) - TRPM (TRPM6) - TRPML (Mucolipin-1) - TRPP - TRPV (TRPV1, TRPV6) |
| Other/general | Gap junction - Stretch-activated ion channel - Ligand-gated ion channel - Voltage-gated ion channel - Cyclic nucleotide-gated ion channel - Two-pore channel |
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