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By definition the neuroimmune system is comprised of the immune system and those components of the nervous system that modulate immune response. In practice, the neuroimmune system also includes hormonal signals and cytokines that participate in signalling between the immune and nervous systems.
Structure
See the article on the immune system for the structure the immune system.
The key components of the nervous system that interact with the immune system are:
- Hypothalamus
- Pituitary gland
- Vagus nerve
The key components of the endocrine system that interact with the immune system are:
- Adrenals
Signals
Hormonal signaling between the nervous system and immune system is provided by:
- Corticosteriods
Cytokine signaling between the nervous system and immune system is provided by:
- Opiods
Overview of Neuro-Immune Interactions
Cytokines regulate immune responses, possibly through activation of the hypothalamic-pituitary-adrenal (HPA) axis.
See also
Further reading
- Berczi and Szentivanyi (2003) NeuroImmune Biology, Elsevier, ISBN 0-444-50851-1 (Written for the higly technical reader)
- Sternberg (2001) The Balance Within, The Science Connecting Health and Emotions, Freeman, ISBN 0-7167-4445-7 (Written for the general public)
Immune system / Immunology / Psychoneuroimmunology
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Systems | Adaptive immune system vs. Innate immune system • Humoral immune system vs. Cellular immune system • Complement system (Anaphylatoxins) |
Antibodies and antigens | Antibody (Monoclonal antibodies, Polyclonal antibodies, Autoantibody) • Allotype • Isotype • Idiotype • Antigen (Superantigen) |
Immune cells | White blood cells (T cell, B cell, NK cell, Mast cell, Basophil, Eosinophil) • Phagocyte (Neutrophil, Macrophage, Dendritic cell) • Antigen-presenting cell • Reticuloendothelial system |
Immunity vs. tolerance | Immunity • Autoimmunity • Allergy • Tolerance (Central) • Immunodeficiency |
Immunogenetics | Somatic hypermutation • V(D)J recombination • Immunoglobulin class switching • MHC / HLA |
Other | Cytokines • Inflammation • Opsonin |
Human anatomy, endocrine system: endocrine glands | |||||||||||||||||||||||||
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Hypothalamic/ pituitary axes |
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Pineal gland |
Pinealocyte · Corpora arenacea | ||||||||||||||||||||||||
Islets of pancreas |
Alpha cell · Beta cell · Delta cell · PP cell · Epsilon cell |
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