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| neuromedin U | |
|---|---|
| Symbol(s): | NMU |
| Locus: | 4 q12 |
| EC number | [1] |
| EntrezGene | 10874 |
| OMIM | 605103 |
| RefSeq | NM_006681 |
| UniProt | P48645 |
Neuromedin U is a neuropeptide which has a number of functions including contraction of smooth muscle.[1]
Neuromedin U exists as multiple isoforms (eg. 25 and 8 amino acids in humans) in some mammals, but only as a single isoform (eg. 23 amino acids in rats) in others. The relative contribution of the different isoforms to the biological function of neuromedin U is generally not well understood. Neuromedin U, like many neuroactive peptides, is amidated at the C-terminus. The sequence of neuromedin U-23 in rats is: YKVNEYNGPVAPSGGFFLFRPRN-(NH2) [1]
See also[]
References[]
- ↑ 1.0 1.1 Brighton PJ, Szekeres PG, Willars GB (2004). Neuromedin U and its receptors: structure, function, and physiological roles. Pharmacol. Rev. 56 (2): 231–48. DOI: 10.1124/pr.56.2.3. PMID: 15169928.
External links[]
Peptides: neuropeptides | |
|---|---|
| Hypothalamic |
Somatostatin - CRH - GnRH - GHRH - Orexins - TRH - POMC (ACTH, MSH, Lipotropin) |
| Gastrointestinal hormones |
Cholecystokinin - Gastric inhibitory polypeptide - Gastrin - Motilin - Secretin - Vasoactive intestinal peptide |
| Other hormones | |
| Other |
Angiotensin - Bombesin/Neuromedin B - Calcitonin gene-related peptide - Carnosine - Delta sleep-inducing peptide - FMRFamide - Galanin - Gastrin releasing peptide - Kinins (Bradykinin, Tachykinins ) - Neuromedin (B, N, U) - Neuropeptide Y - Neurophysins - Neurotensin - Opioid peptide - Pancreatic polypeptide - Pituitary adenylate cyclase activating peptide |
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