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Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)
| neuropeptide FF receptor 1 | |
|---|---|
| Symbol(s): | NPFFR1 GPR147 |
| Locus: | 10 q21-q22 |
| EC number | [1] |
| EntrezGene | 64106 |
| OMIM | 607448 |
| RefSeq | NM_022146 |
| UniProt | Q9GZQ6 |
| neuropeptide FF receptor 2 | |
|---|---|
| Symbol(s): | NPFFR2 GPR74 |
| Locus: | 4 q21 |
| EC number | [2] |
| EntrezGene | 10886 |
| OMIM | 607449 |
| RefSeq | NM_004885 |
| UniProt | Q9Y5X5 |
The neuropeptide FF receptors[1] are members of the G-protein coupled receptor superfamily of integral membrane proteins which bind the pain modulatory neuropeptides AF and FF.[2][3]
References[]
- ↑ Parker RM, Copeland NG, Eyre HJ, Liu M, Gilbert DJ, Crawford J, Couzens M, Sutherland GR, Jenkins NA, Herzog H (2000). Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. Brain Res. Mol. Brain Res. 77 (2): 199–208.
- ↑ Elshourbagy NA, Ames RS, Fitzgerald LR, Foley JJ, Chambers JK, Szekeres PG, Evans NA, Schmidt DB, Buckley PT, Dytko GM, Murdock PR, Milligan G, Groarke DA, Tan KB, Shabon U, Nuthulaganti P, Wang DY, Wilson S, Bergsma DJ, Sarau HM (2000). Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J. Biol. Chem. 275 (34): 25965–71.
- ↑ Mollereau C, Mazarguil H, Marcus D, Quelven I, Kotani M, Lannoy V, Dumont Y, Quirion R, Detheux M, Parmentier M, Zajac JM (2002). Pharmacological characterization of human NPFF(1) and NPFF(2) receptors expressed in CHO cells by using NPY Y(1) receptor antagonists. Eur. J. Pharmacol. 451 (3): 245–56.
External links[]
- Neuropeptide FF Receptors. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
- MeSH neuropeptide+FF+receptor
Neuropeptide receptors | |
|---|---|
| Hypothalamic hormone receptors |
CRH - FSH - LHRH - TRH - Somatostatin |
| Pituitary hormone receptors |
Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - Type I cytokine receptor (GH, Prolactin) - TSH |
| Other hormone receptors |
Atrial natriuretic factor - Calcitonin - Cholecystokinin - VIP |
| Opioid receptors |
Delta - Kappa - Mu - Sigma (1, 2) - Nociceptin |
| Other neuropeptide receptors |
Angiotensin - Bradykinin/Tachykinin (TACR1) - Calcitonin gene-related peptide - Galanin - GPCR neuropeptide (B/W, FF, S, Y) - Neurotensin |
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