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calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | |
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Symbol(s): | CACNA1A CACNL1A4, SCA6, MHP1, MHP |
Locus: | 19 p13 |
EC number | [1] |
EntrezGene | 773 |
OMIM | 601011 |
RefSeq | NM_000068 |
UniProt | O00555 |
The p-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties.
P-type ('P' for purkinje fibers) calcium channels play a similar role to the N-type calcium channel in neurotransmitter release at the presynaptic terminal, but are found in purkinje cells in the electrical conduction system of the heart. Their properties are less well understood.
External links[]
Membrane transport protein: ion channels
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Ca | Voltage-dependent calcium channel (L-type/CACNA1C, N-type, P-type, Q-type, R-type, T-type) - Inositol triphosphate receptor - Ryanodine receptor - Cation channels of sperm |
Na: Sodium channel | Nav1.4 - Nav1.5 - Nav1.7 - Epithelial sodium channel |
K: Potassium channel | Voltage-gated (KvLQT1, KvLQT2, KvLQT3, HERG, Shaker gene, KCNE1) - Calcium-activated (BK channel, SK channel) - Inward-rectifier (ROMK, KCNJ2) - Tandem pore domain |
Cl: Chloride channel | Cystic fibrosis transmembrane conductance regulator |
Porin | Aquaporin (1, 2, 3, 4) |
Transient receptor potential | TRPA - TRPC (TRPC6) - TRPM (TRPM6) - TRPML (Mucolipin-1) - TRPP - TRPV (TRPV1, TRPV6) |
Other/general | Gap junction - Stretch-activated ion channel - Ligand-gated ion channel - Voltage-gated ion channel - Cyclic nucleotide-gated ion channel - Two-pore channel |
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