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Phendimetrazine chemical structure

IUPAC name
CAS number
ATC code


Chemical formula {{{chemical_formula}}}
Molecular weight 191.27
Bioavailability Peak plasma levels occur within 1 to 3 hours. Absorption is usually complete by 4 to 6 hours
Metabolism hepatic
Elimination half-life 19-24 hours
Excretion Urinary elimination
Pregnancy category C (US)
Legal status C-III (US)
Routes of administration Oral
Indicated for:

Phendimetrazine (Bontril®) is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances. In the United States, phendimetrazine is a Schedule III controlled substance under the Uniform Controlled Substances Act of 1970.

Phendimetrazine is used clinically in the form of phendimetrazine tartrate.


Approximately 30% of a given dose of phendimetrazine is metabolized into phenmetrazine, which may account for part of its anorectic effect, and probably also influences abuse potential; individuals who metabolise a greater proportion of phendimetrazine into phenmetrazine are more likely to develop problems with dependence and addiction.

According to the "List of psychotropic substances under international control," phendimetrazine is a Schedule IV controlled substance.[How to reference and link to summary or text]

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