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Principles of Neural Science cover

First published in 1981 by Elsevier, Principles of Neural Science is a neuroscience textbook edited by Eric R. Kandel, James Schwartz, and Thomas Jessell. The original edition was 468 pages; now on the fourth edition, the book has grown to 1414 pages. The second edition was published in 1985, third in 1991, fourth in 2000, with the fifth edition due for publication in October 2007.




Including the three editors—all of whom also contributed to individual chapters in the book—there are a total of 45 authors of this text. Included among there are several notable researchers and physicians. Several authors are also highly decorated scientists, including Nobel laureate Linda B. Buck.


Principles of Neural Science is often assigned as a textbook for many undergraduate and graduate neuroscience and neurobiology courses. The book attempts to at least introduce every aspect of the modern understanding of the biology of the brain. The fourth edition is divided into nine parts:


  • Kandel ER, Schwartz JH, Jessell TM 2000. Principles of Neural Science, 4th ed. McGraw-Hill, New York. ISBN 0-8385-7701-6
  • Kandel ER et al 2007. 5th ed. ISBN 0071390111