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A sequela, (pronounced /sɨˈkwiːlə/, plural sequelæ) is a pathological condition resulting from a disease, injury, or other trauma.

Post-traumatic stress disorder may be a psychological sequela of rape. Sequelae of traumatic brain injury include headache and dizziness, anxiety, apathy, depression, aggression, cognitive impairments, personality changes, mania, psychosis. Typically, a sequela is a chronic condition that is a complication of an acute condition that begins during the acute condition. This is in contrast to a late effect.

Some conditions may be diagnosed retrospectively from their sequelae.